An ensemble medical show about a group of ex-Army doctors who work the night shift at a hospital and do whatever it takes to help their patients. Using battlefield-tested medical skills, doctors clash with hospital bureaucrats who are more worried about the bottom line than the lives of their patients.

Life in the emergency room at San Antonio Memorial is never routine, and the men and women that make up the night shift team are a special breed. The new season finds the crew still recovering from a shocking hostage situation that left one of their colleagues dead. The experience brought them all a little closer but also exposed some personal weaknesses.